A new player in the dynamic instability of microtubules – Scivit News: Structure and growth of the microtubule cytoskeleton is determined by the interplay of slow buildup and rapid („catastrophic“) disintegration.
Damage within microtubule can be repaired by the integration of tubulin; repair-sites stabilize microtubuls agains catastrophic disintegration.
Repair-sites are particularly numerous close to microtubule crossings, bundles or places under physical stress shifting the buildup/disintegration balance toward buildup in those places.
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